Selective targeting of CCNE1 using molecular glue degraders for the treatment of CCNE1 amplified cancers ... CCNE1 (Cyclin E1) is a Target for Solid Tumors with Deregulated Cyclin E1 ... First-in-class Cyclin E1 degraders for CCNE1 ... CCNE1 ... CCNE1.K118 ... CCNE1.